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mGluR5 Recombinant Monoclonal Antibody, APC-Cy5 Conjugated

Applications

  • WB

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-61218r-apc-cy5-100ul
Product Name mGluR5 Recombinant Monoclonal Antibody, APC-Cy5 Conjugated
Applications WB
Reactivity Human, Mouse, Rat
Specifications
Conjugation APC-Cy5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human mGluR5
Clonality Monoclonal
Clone # Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 2915
Swiss Prot P41594
Subcellular location Cell membrane
Synonyms GPRC1E; GRM5; Metabotropic glutamate receptor 5 precursor; MGLUR5; MGR5.
Background G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.
Application Dilution
WB =1:500-2000