Bcl-XL Recombinant Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61072r-100ul |
| Product Name | Bcl-XL Recombinant Antibody |
| Applications | WB |
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Bcl-xL |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Storage Condition | Store at 4°C for short term. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 598 |
| Swiss Prot | Q07817 |
| Subcellular location | Cytoplasm, Nucleus, Cell membrane |
| Synonyms | Apoptosis regulator Bcl X; BclX; Bcl-X; Bcl 2 like 1; Bcl 2 like 1 protein; Bcl xL; BCL X/L; BCL XL/S; Bcl xS; Bcl2 like1; BCL2-related gene; BCL2-related protein, long isoform, included; BCLXL, included; BCL2-related protein, short isoform, included; BCLXS, included; BCL2L; Bclx; DKFZp781P2092; MGC113803; MGC99998; B2CL1_HUMAN. |
| Background | Potent inhibitor of cell death. Inhibits activation of caspases (By similarity). Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane.
Isoform Bcl-X(S) promotes apoptosis. |
| Application Dilution | |
| WB | 1:300-5000 |
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