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Phospho-EGFR(Y1068) Monoclonal Antibody

Applications

  • WB
  • FCM
  • IF(ICC)
  • IP

Reactivity

  • Human
Overview
Catalog # bsm-54587R
Product Name Phospho-EGFR(Y1068) Monoclonal Antibody
Applications WB, FCM, IF(ICC), IP
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source Synthetic phospho-Peptide corresponding to residues surrounding Tyr1068 of human EGFR.
Modification Site Tyr1068
Clonality Monoclonal
Clone # 1H2
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 1956
Swiss Prot P00533
Subcellular location Nucleus, Secreted, Cell membrane, Endosome, Endoplasmic reticulum membrane, Golgi apparatus membrane, Nucleus membrane
Synonyms Avian erythroblastic leukemia viral (v erb b) oncogene homolog antibody, Cell growth inhibiting protein 40 antibody, Cell proliferation inducing protein 61 antibody, EGF R antibody, EGFR antibody, EGFR_HUMAN antibody, Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog) antibody, Epidermal growth factor receptor (erythroblastic leukemia viral (v erb b) oncogene homolog avian) antibody, Epidermal growth factor receptor antibody, erb-b2 receptor tyrosine kinase 1 antibody, ERBB antibody, ERBB1 antibody, Errp antibody, HER1 antibody, mENA antibody, NISBD2 antibody, Oncogen ERBB antibody, PIG61 antibody, Proto-oncogene c-ErbB-1 antibody, Receptor tyrosine protein kinase ErbB 1 antibody, Receptor tyrosine-protein kinase ErbB-1 antibody, SA7 antibody, Species antigen 7 antibody, Urogastrone antibody, v-erb-b Avian erythroblastic leukemia viral oncogen homolog antibody, wa2 antibody, Wa5 antibody
Background The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Application Dilution
WB 1:300-5000
FCM 1:20-100
IF(ICC) 1:50-200
IP 1-2ug