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ACE2 Monoclonal Antibody

Applications

  • WB
  • IHC-P
  • IF(ICC)
  • IP
  • IHC

Reactivity

  • Human
  • Mouse
  • Rat
  • Hamster
Overview
Catalog # bsm-54571R
Product Name ACE2 Monoclonal Antibody
Applications WB, IHC-P, IF(ICC), IP, IHC
Reactivity Human, Mouse, Rat, Hamster
Specifications
Conjugation Unconjugated
Host Rabbit
Source Synthetic Peptide within Human ACE2 aa 200-230.
Clonality Monoclonal
Clone # 3B5
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 59272
Swiss Prot Q9BYF1
Subcellular location Cytoplasm, Secreted, Cell membrane
Synonyms ACE 2 antibody, ACE related carboxypeptidase antibody, ACE-related carboxypeptidase antibody, ACE2 antibody, ACE2_HUMAN antibody, ACEH antibody, Angiotensin converting enzyme 2 antibody, Angiotensin converting enzyme homolog antibody, Angiotensin converting enzyme like protein antibody, Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2 antibody, Angiotensin I converting enzyme 2 antibody, Angiotensin-converting enzyme homolog antibody, DKFZP434A014 antibody, EC 3.4.17 antibody, metalloprotease MPROT 15 antibody, Metalloprotease MPROT15 antibody, OTTHUMP00000022963 antibody, Processed angiotensin-converting enzyme 2 antibody
Background Angiotensin converting enzyme 2 (ACE2) is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin[1-9], or the conversion of angiotensin II to angiotensin 1-7. ACE2 has direct effects on cardiac function,a and is expressed predominantly in vascular endothelial cells of the heart and the kidneys. ACE2 is not sensitive to the ACE inhibitor drugs used to treat hypertension. ACE2 receptors have been shown to be the entry point into human cells for some coronaviruses, including the SARS virus[10]. A number of studies have identified that the entry point is the same for SARS-CoV-2, the COVID-19 virus.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IP 1-2ug
IHC