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Phospho-STAT1(S727) Monoclonal Antibody

Applications

  • WB
  • IHC-P
  • IHC

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-54561R
Product Name Phospho-STAT1(S727) Monoclonal Antibody
Applications WB, IHC-P, IHC
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source Recombinant protein
Modification Site Ser727
Clonality Monoclonal
Clone # 28E3
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 6772
Swiss Prot P42224
Subcellular location Cytoplasm, Nucleus
Synonyms Signal transducer and activator of transcription 1 91kD antibody, CANDF7 antibody, DKFZp686B04100 antibody, IMD31A antibody, IMD31B antibody, IMD31C antibody, ISGF 3 antibody, ISGF-3 antibody, OTTHUMP00000163552 antibody, OTTHUMP00000165046 antibody, OTTHUMP00000165047 antibody, OTTHUMP00000205845 antibody, Signal transducer and activator of transcription 1 91kDa antibody, Signal transducer and activator of transcription 1 antibody, Signal transducer and activator of transcription 1, 91kD antibody, Signal transducer and activator of transcription 1-alpha/beta antibody, STAT 1 antibody, Stat1 antibody, STAT1_HUMAN antibody, STAT91 antibody, Transcription factor ISGF 3 components p91 p84 antibody, Transcription factor ISGF-3 components p91/p84 antibody
Background The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IHC