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GNL3 (6H5) Monoclonal Antibody

Applications

  • FCM
  • IHC-P
  • IF(IHC-P)
  • IF(ICC)

Reactivity

  • Human
Overview
Catalog # bsm-54389R
Product Name GNL3 (6H5) Monoclonal Antibody
Applications FCM, IHC-P, IF(IHC-P), IF(ICC)
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source Recombinant protein corresponding to the C-terminus of human Nucleostemin.
Clonality Monoclonal
Clone # 6H5
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition Store at 4C for up to 2 weeks. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Target
Gene ID 26354
Swiss Prot Q9BVP2
Subcellular location Nucleus
Synonyms Guanine nucleotide-binding protein-like 3; E2-induced gene 3 protein; Novel nucleolar protein 47; Nucleolar GTP-binding protein 3; Nucleostemin; NNP47; GNL3; E2IG3;
Background May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation. May interact with p53 and may be involved in tumorigenesis. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for this gene
Application Dilution
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200