DEK (1C7) Monoclonal Antibody

$Lane 1: A431 Cells; Probed with DEK (1C7) Monoclonal Antibody (bsm-54339R) at 1:500 overnight at 4\u00b0C followed by a conjugated secondary antibody for 60 minutes at 37\u00b0C.$

Lane 1: A431 Cells; Probed with DEK (1C7) Monoclonal Antibody (bsm-54339R) at 1:500 overnight at 4\u00b0C followed by a conjugated secondary antibody for 60 minutes at 37\u00b0C.

Applications

WB
IF(ICC)

Reactivity

Human

Overview
Catalog #	bsm-54339R
Product Name	DEK (1C7) Monoclonal Antibody
Applications	WB, IF(ICC)
Reactivity	Human
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	Recombinant protein corresponding to C-terminal human DEK.
Clonality	Monoclonal
Clone #	1C7
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition	Store at 4C for up to 2 weeks. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Target
Gene ID	7913
Swiss Prot	P35659
Subcellular location	Nucleus
Synonyms	Protein DEK; DEK; DEK proto-oncogene; D6S231E
Background	DEK has one SAP domain. DEK binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene.
Application Dilution
WB	1:300-5000
IF(ICC)	1:50-200