Overview |
bsm-54333R |
Thrombomodulin (3G7) Monoclonal Antibody |
WB, IHC-P, IF(ICC) |
Human |
Specifications |
Unconjugated |
Rabbit |
Recombinant protein corresponding to the C-terminus of human Thrombomodulin |
Monoclonal |
3G7 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at 4C for up to 2 weeks. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Target |
7056 |
P07204 |
Cell membrane |
Thrombomodulin; Fetomodulin; CD141; TM; THBD; THRM; AHUS6; BDCA3; THPH12 |
Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |
IF(ICC) |
1:50-200 |