MMP3 (3C5) Monoclonal Antibody

$Lane 1: Human Liver; Lane 2: Mouse Lung; Lane 3: Rat Liver; Probed with MMP3 (3C5) Monoclonal Antibody (bsm-54152R) at 1:1000 overnight at 4\u00b0C followed by a conjugated secondary antibody for 60 minutes at 37\u00b0C.$

Lane 1: Human Liver; Lane 2: Mouse Lung; Lane 3: Rat Liver; Probed with MMP3 (3C5) Monoclonal Antibody (bsm-54152R) at 1:1000 overnight at 4\u00b0C followed by a conjugated secondary antibody for 60 minutes at 37\u00b0C.

$Paraformaldehyde-fixed and paraffin-embedded Rat Kidney tissue incubated MMP3 (3C5) Monoclonal Antibody (bsm-54152R) at 1:100, overnight at 4\u00b0C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.$

Paraformaldehyde-fixed and paraffin-embedded Rat Kidney tissue incubated MMP3 (3C5) Monoclonal Antibody (bsm-54152R) at 1:100, overnight at 4\u00b0C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.

$Paraformaldehyde-fixed and paraffin-embedded Human Liver tissue incubated MMP3 (3C5) Monoclonal Antibody (bsm-54152R) at 1:100, overnight at 4\u00b0C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.$

Paraformaldehyde-fixed and paraffin-embedded Human Liver tissue incubated MMP3 (3C5) Monoclonal Antibody (bsm-54152R) at 1:100, overnight at 4\u00b0C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.

$Paraformaldehyde-fixed and paraffin-embedded Human Placenta tissue incubated MMP3 (3C5) Monoclonal Antibody (bsm-54152R) at 1:100, overnight at 4\u00b0C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.$

Paraformaldehyde-fixed and paraffin-embedded Human Placenta tissue incubated MMP3 (3C5) Monoclonal Antibody (bsm-54152R) at 1:100, overnight at 4\u00b0C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.

$Paraformaldehyde-fixed and paraffin-embedded Mouse Liver tissue incubated MMP3 (3C5) Monoclonal Antibody (bsm-54152R) at 1:100, overnight at 4\u00b0C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.$

Paraformaldehyde-fixed and paraffin-embedded Mouse Liver tissue incubated MMP3 (3C5) Monoclonal Antibody (bsm-54152R) at 1:100, overnight at 4\u00b0C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.

Applications

WB
IHC-P

Reactivity

Human
Mouse
Rat

Overview
Catalog #	bsm-54152R
Product Name	MMP3 (3C5) Monoclonal Antibody
Applications	WB, IHC-P
Reactivity	Human, Mouse, Rat
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	Recombinant protein within C-terminal human MMP3
Clonality	Monoclonal
Clone #	3C5
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition	Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	4314
Swiss Prot	P08254
Subcellular location	Secreted
Synonyms	Stromelysin-1; Matrix metalloproteinase-3; Transin-1; SL-1; MMP-3; MMP3; STR1; CHDS6; STMY1.
Background	Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP3 is an enzyme which degrades fibronectin, laminin, gelatins of type I, III, IV, and V, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, the progression of atherosclerosis, activation of procollagenase and tumor initiation.
Application Dilution
WB	1:300-5000
IHC-P	1:200-400