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Dynein intermediate chain 1 (3A1) Monoclonal Antibody

Applications

  • FCM
  • IHC-P

Reactivity

  • Mouse
Overview
Catalog # bsm-54134R
Product Name Dynein intermediate chain 1 (3A1) Monoclonal Antibody
Applications FCM, IHC-P
Reactivity Mouse
Specifications
Conjugation Unconjugated
Host Rabbit
Source Human Dynein intermediate chain 1 aa 1-200
Clonality Monoclonal
Clone # 3A1
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition Store at 4C for up to 2 weeks. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Target
Gene ID 27019
Swiss Prot Q9UI46
Synonyms Dynein intermediate chain 1 axonemal; Axonemal dynein intermediate chain 1; DNAI1; CILD1.
Background This gene encodes a member of the dynein intermediate chain family. The encoded protein is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome. Alternative splicing results in multiple transcript variants.
Application Dilution
FCM 1:20-100
IHC-P 1:200-400