Overview |
bsm-53000M |
RbAp 46/48 Monoclonal Antibody |
WB, IF(ICC) |
Human |
Specifications |
Unconjugated |
Mouse |
Monoclonal antibody raised in mouse against the full length human RbAp48 protein (Retinoblastoma-binding protein p48) fused to GST. The antibody recognizes both RbAp48 and RbAp46 |
Monoclonal |
6D1 |
IgG2b |
Not Determined |
Ascites fluid from mouse containing 0.05% azide |
Ascites fluid with 0.05% sodium azide. |
Store at -20°C for 12 months. |
Target |
5928 |
Q09028 |
Histone-binding protein RBBP4, RBBP4, p48, RBBP-4, RBAP48 |
Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex. |
Application Dilution |
WB |
1:300-5000 |
IF(ICC) |
1:50-200 |