Overview |
bsm-52303R |
Caveolin-1 (9C11) Monoclonal Antibody |
WB, IHC-P, IF(IHC-P), IF(ICC) |
Human, Mouse |
Specifications |
Unconjugated |
Rabbit |
Human Caveolin-1 aa 100-250 |
Monoclonal |
9C11 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at -20°C for 12 months. |
Target |
857 |
Q03135 |
Cell membrane, Golgi apparatus |
Caveolin-1; CAV1; CAV |
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |
IF(IHC-P) |
1:50-200 |
IF(ICC) |
1:50-200 |