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UCHL1/PGP9.5 Monoclonal Antibody

Applications

  • WB
  • IHC-P

Reactivity

  • Xenopus laevis

Predicted Reactivity

  • Human
  • Mouse
  • Rat
  • Cow
  • Pig
  • Monkey
Overview
Catalog # bsm-51558M
Product Name UCHL1/PGP9.5 Monoclonal Antibody
Applications WB, IHC-P
Reactivity Xenopus laevis
Predicted Reactivity Human, Mouse, Rat, Cow, Pig, Monkey
Specifications
Conjugation Unconjugated
Host Mouse
Source KLH conjugated synthetic peptide derived from human UCHL1/PGP9.5
Immunogen Range 151-223/223
Clonality Monoclonal
Clone # T2F5
Isotype IgG1
Concentration 0.5ug/ul
Purification Purified by Protein G.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 7345
Swiss Prot P09936
Subcellular location Cytoplasm, Cell membrane
Synonyms Gracile axonal dystrophy; Neuron cytoplasmic protein 9.5; Park 5; Park5; Parkinson Disease 5; PGP 9.5; PGP95; Protein gene product 9.5; Ubiquitin C terminal esterase L1; Ubiquitin C terminal hydrolase (neuron specific); Ubiquitin C terminal hydrolase; Ubiquitin carboxyl terminal esterase L1; Ubiquitin carboxyl terminal hydrolase isozyme L1; Ubiquitin carboxyl-terminal hydrolase isozyme L1; Ubiquitin thioesterase L1; Ubiquitin thiolesterase; Ubiquitin thiolesterase L1; UCH L1; UCH-L1; UCHL1; UCHL1_HUMAN.
Background Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.
Application Dilution
WB =1:500-1000,IHC-P=1:25-50,
IHC-P 1:200-400