Glucocorticoid receptor Monoclonal Antibody

$Lane 1: Jurkat cell lysates; Lane 2: HepG2 cell lysates; Lane 3: NIH\/3T3 cell lysates; Lane 4: Mouse Liver tissue lysates probed with Glucocorticoid receptor Monoclonal Antibody, Unconjugated (bsm-51554M) at 1:1000 dilution and 4\u00b0C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.$

Lane 1: Jurkat cell lysates; Lane 2: HepG2 cell lysates; Lane 3: NIH\/3T3 cell lysates; Lane 4: Mouse Liver tissue lysates probed with Glucocorticoid receptor Monoclonal Antibody, Unconjugated (bsm-51554M) at 1:1000 dilution and 4\u00b0C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.

Applications

Predicted Reactivity

Human
Mouse

Overview
Catalog #	bsm-51554M
Product Name	Glucocorticoid receptor Monoclonal Antibody
Applications	WB
Predicted Reactivity	Human, Mouse
Specifications
Conjugation	Unconjugated
Host	Mouse
Source	KLH conjugated synthetic peptide derived from human Glucocorticoid receptor
Immunogen Range	101-200/444
Clonality	Monoclonal
Clone #	G4H12
Concentration	0.5ug/ul
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	290
Swiss Prot	P04150
Subcellular location	Cytoplasm, Nucleus
Synonyms	NR3C1; glucocorticoid receptor isoform alpha; GCCR; GCR; GR; Nuclear receptor subfamily 3 group C member 1; Glucocorticoid receptor lymphocyte; GRL; Grl1; GCR_HUMAN.
Background	Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. Involved in nuclear translocation.
Application Dilution
WB	=1:500-1000Ôºå