Overview |
bsm-51407M |
CBX8 (12C7) Monoclonal Antibody |
WB |
Human |
Specifications |
Unconjugated |
Mouse |
This CBX8 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between amino acids from the C-terminal region of human CBX8. |
Monoclonal |
12C7 |
IgG1 |
0.5ug/ul |
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
57332 |
Q9HC52 |
PC3; RC1; Chromobox protein homolog 8; Polycomb 3 homolog; hPc3; Rectachrome 1; CBX8 |
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. |
Application Dilution |
WB |
1:300-5000 |