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NFKBIA (1C1) Monoclonal Antibody

Applications

  • WB

Reactivity

  • Human
  • Mouse
Overview
Catalog # bsm-51393M
Product Name NFKBIA (1C1) Monoclonal Antibody
Applications WB
Reactivity Human, Mouse
Specifications
Conjugation Unconjugated
Host Mouse
Source Purified His-tagged NFKBIA protein was used to produced this monoclonal antibody.
Clonality Monoclonal
Clone # 1C1
Isotype IgG1
Concentration 0.5ug/ul
Purification Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 4792
Swiss Prot P25963
Synonyms IKBA; MAD-3; NFKBI; NF-kappa-B inhibitor alpha; I-kappa-B-alpha; IkB-alpha; IkappaBalpha; Major histocompatibility complex enhancer-binding protein MAD3; NFKBIA; MAD3
Background Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Application Dilution
WB 1:300-5000