| Overview |
| bsm-51068M |
| MAP3K11 (3T1) Monoclonal Antibody |
| WB |
| Human |
| Specifications |
| Unconjugated |
| Mouse |
| This MAP3K11 monoclonal antibody is generated from mouse immunized with MAP3K11 recombinant protein. |
| Monoclonal |
| 3T1 |
| IgM |
| 0.5ug/ul |
| Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 4296 |
| Q16584 |
| MLK3; PTK1; SPRK; MLK-3; MEKK11; Mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase; MAP3K11 |
| Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle. |
| Application Dilution |
| WB |
1:300-5000 |
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