SARS-CoV-2 Nucleocapsid monoclonal Antibody

Applications

ELISA

Reactivity

SARS-CoV-2

Overview
Catalog #	bsm-41488M
Product Name	SARS-CoV-2 Nucleocapsid monoclonal Antibody
Applications	ELISA
Reactivity	SARS-CoV-2
Specifications
Conjugation	Unconjugated
Host	Mouse
Source	Recombinant SARS-CoV-2 Nucleocapsid Protein:1-419/419
Immunogen Range	1-419/419
Clonality	Monoclonal
Clone #	8C8
Isotype	IgG2a
Concentration	1mg/ml
Purification	Purified by Protein G.
Storage Buffer	Aqueous buffered solution containing 0.01M PBS(pH7.4) with 0.1% Proclin300.
Storage Condition	Store at -20°C for 12 months.
Target
Gene ID	43740575
Swiss Prot	P0DTC9
Synonyms	SARS-CoV-2 Nucleocapsid Protein; SARS-CoV-2 NP; nucleocapsid protein [Severe acute respiratory syndrome coronavirus 2]; novel coronavirus N Protein; novel coronavirus Nucleocapsid Protein; 2019-nCoV Nucleoprotein; 2019-nCoV N; 2019nCoV N; 2019-nCoV N Protein; 2019 ncov N Protein; 2019-nCoV nucleocapsid protein.
Background	Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Application Dilution
ELISA	1:500-1000