| Overview |
| bsm-33193M-Cy3 |
| Cytochrome C (6B10) Monoclonal Antibody, Cy3 Conjugated |
| WB, IF(IHC-P) |
| Human, Rat, Rabbit |
| Specifications |
| Cy3 |
| Mouse |
| Recombinant human Cytochrome C Protein |
| Monoclonal |
| 6B10 |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 54205 |
| P99999 |
| Cytochrome c; CYCS |
| Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. |
| Application Dilution |
| WB |
|
| IF(IHC-P) |
1:50-200 |
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