Overview |
bsm-33097M-Cy3 |
Histone H3 (tri methyl K79) Monoclonal Antibody, Cy3 Conjugated |
WB, IF(IHC-P), IF(ICC) |
Human, Mouse, Rat |
Specifications |
Cy3 |
Mouse |
KLH conjugated synthetic peptide derived from human Histone H3 (tri methyl K79) |
Monoclonal |
5A6 |
IgG1 |
1ug/ul |
Purified by Protein G. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
8290 |
Q16695 |
Nucleus |
Histone Cluster 3, H3; H3 Histone Family, Member T; Histone 3, H3; H3FT; H3/G; H3/T; H3t; H3.4 ; Histone H3.1t ; HIST3H3; HGNC:4778; H31T_HUMAN |
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |
IF(ICC) |
1:50-200 |