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mouse Ly-49C/F/H/I/PE

Applications

  • FCM

Reactivity

  • Mouse
Overview
Catalog # bsm-30282h-pe-100t
Product Name mouse Ly-49C/F/H/I/PE
Applications FCM
Reactivity Mouse
Specifications
Conjugation Unconjugated
Host Hamster
Clonality Monoclonal
Clone # 3F12
Isotype IgG1
Concentration n/a
Purification Affinity purified by Protein G
Storage Buffer 0.01M PBS, 0.5%BSA, 0.02% Proclin300
Storage Condition Store at 2-8°C
Target
Gene ID 16634.0
Swiss Prot Q64329
Synonyms KLRA3_MOUSE; 5E6; Killer cell lectin like receptor 3; Killer cell lectin like receptor subfamily A member 3; KLRA 3; Ly 49c; Ly49C; Lymphocyte antigen 49c; MGC123910; Natural killer cell associated antigen 2; Nk 2; NK 2.1; Nk2; Nk2.1; OTTMUSP00000026267; T cell surface glycoprotein Ly 49C.
Background KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide–receptive H-2Kb.
Application Dilution
FCM 10ul/10^6 cells in 100ul