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human CD178/FITC

Applications

  • FCM

Reactivity

  • Human
Overview
Catalog # bsm-30138M-FITC
Product Name human CD178/FITC
Applications FCM
Reactivity Human
Specifications
Conjugation Unconjugated
Host Mouse
Clonality Monoclonal
Clone # 4A3
Isotype IgG1/Kappa
Concentration n/a
Purification Affinity purified by Protein G
Storage Buffer 0.01M PBS, 0.5%BSA, 0.03% Proclin300
Storage Condition Store at 2-8℃. Protect from light. Avoid freezing.
Target
Gene ID 356
Swiss Prot P48023
Synonyms Tumor necrosis factor ligand superfamily member 6; FASLG; APO1L; Apoptosis (APO 1) antigen ligand 1; Fas-L; Apoptosis antigen ligand 1; APTL; CD178; CD-178; CD 178; CD95L; CD95 ligand; CD95-L; CD95L protein; FAS antigen ligand; Fas L; FASL; Fas ligand (TNF superfamily member 6); Generalized lymphoproliferative disease; TNF superfamily member 6; TNFSF6; TNFL6_HUMAN; Apoptosis antigen ligand; Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form; FASLG.
Background This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014]
Application Dilution
FCM 1:20-100