Overview |
bs-9737R-APC |
EDRF1 Polyclonal Antibody, APC Conjugated |
WB, IF(IHC-P) |
Human, Mouse, Rat |
Specifications |
APC |
Rabbit |
KLH conjugated synthetic peptide derived from human EDRF1/C10orf137 |
101-200/1238 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
26098 |
C10orf137 protein; Chromosome 10 open reading frame 137; EDRF1; Erythroid dferentiation related factor 1; EDRF1_HUMAN. |
The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways. At the sequence level, there can be up to 16 tandem TPR repeats, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity. EDRF1 (erythroid differentiation-related factor 1), also known as C10orf137 (chromosome 10 open reading frame 137), is a 1,238 amino acid protein containing two TPR repeats. Localizing to nucleus, EDRF1 is involved in transcriptional activation of globin genes by regulating DNA-binding activity of GATA-1 transcription factor. EDRF1 may also play an important role in organ development and histological differentiation. EDRF1 exists as four alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 10q26.13. |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |