IFI35 Polyclonal Antibody, APC-Cy5.5 Conjugated
Applications
Reactivity
Overview | |
Catalog # | bs-9704R-APC-Cy5.5 |
Product Name | IFI35 Polyclonal Antibody, APC-Cy5.5 Conjugated |
Applications | WB, IF(IHC-P) |
Reactivity | Human, Mouse, Rat |
Specifications | |
Conjugation | APC-Cy5.5 |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from human IFI35 |
Immunogen Range | 101-200/286 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target | |
Gene ID | 3430 |
Synonyms | I 35; i-35; I35; P 35; P35; IN35; IN35_HUMAN; Interferon induced 35 kDa protein; Interferon-induced 35 kDa protein. |
Background | The Interferon family of proteins are able to alter the expression of a variety of target genes, thereby controlling various events within the cell. IFI-35 (Interferon-induced 35 kDa protein), also known as IFP35, is a 286 amino acid interferon-induced protein. Localized to the nucleus and expressed in macrophages, fibroblasts and epithelial cells, IFI-35 is a leucine zipper protein that can form homodimers, but, unlike most leucine zipper proteins, cannot bind DNA. Upon induction by IFN-? IFI-35 associates with Nmi (N-Myc-interacting protein), resulting in the formation of a high molecular weight complex that is thought to play a role in IFN-?signaling and cellular responses. Once complexed with Nmi, IFI-35 is unable to be degraded by the proteasome, suggesting that IFI-35 is protected from degradation only when needed by IFN-? Two isoforms of IFI-35 exist due to alternative splicing events. |
Application Dilution | |
WB | 1:300-5000 |
IF(IHC-P) | 1:50-200 |