| Overview |
| bs-9214R-Cy7 |
| SERPINB3 + SERPINB4 Polyclonal Antibody, Cy7 Conjugated |
| WB, IF(IHC-P) |
| Human |
| Specifications |
| Cy7 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human SERPINB3 (same as SERPINB4) |
| 71-170/390 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 6317 |
| HsT1196; Protein T4 A; Protein T4-A; SCC; SCCA PD; SCCA-1; SCCA1; SCCAPD; Serine or cysteine proteinase inhibitor clade B ovalbumin member 3; Serpin B3; Serpin peptidase inhibitor clade B ovalbumin member 3; SERPINB3; SPB3_HUMAN; Squamous cell carcinoma antigen 1; T4 A; T4A; SCCA 2; SCCA2; Leupin; Peptidase inhibitor 11; PI 11; PI-11; PI11; Protease inhibitor leucine serpin; SCCA-2; SCCA1; SCCA2/SCCA1 fusion protein; Serine or cysteine proteinase inhibitor, clade B ovalbumin, member 4; Serpin B4; Serpin peptidase inhibitor, clade B ovalbumin, member 4; SERPINB 4; SERPINB4; SPB4_HUMAN; Squamous cell carcinoma antigen 1; Squamous cell carcinoma antigen 2. |
| Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins. Among the proteins mediating metastasis are serine prote-ases, such as neutrophil elastase.SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1. The human SCCA1 gene encodes a 390 amino acid protein that was originally isolated from a metastatic cervical squamous cell carcinoma. SCCA2 may act as a protease inhibitor to modulate the host immune response against tumor cells. |
| Application Dilution |
| WB |
1:300-5000 |
| IF(IHC-P) |
1:50-200 |
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