Overview |
bs-9097R-Cy7 |
ANKS1B Polyclonal Antibody, Cy7 Conjugated |
WB, IF(IHC-P) |
Human, Mouse, Rat |
Specifications |
Cy7 |
Rabbit |
KLH conjugated synthetic peptide derived from human ANKS1B/AIDA1 |
851-1000/1248 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
56899 |
Q7Z6G8 |
AIDA 1; AIDA-1; Amyloid-beta protein intracellular domain-associated protein 1; Anks1b; Ankyrin repeat and sterile alpha mot domain-containing protein 1B; ANS1B_HUMAN; E2A-PBX1-associated protein; EB-1. |
The _-Amyloid protein precursor (AbPP) is a widely expressed transmembrane protein that is processed into the b-Amyloid (Ab) peptide, which accumulates in insoluble plaques in the brain of Alzheimer?s disease patients and AbPP intracellular domain (AID). AID may function as a pro-apoptotic peptide, a regulator of calcium homeostasis and a molecule involved in transcriptional regulation. The AID associated protein 1 (AIDA-1) is highly expressed in the brain and is regulated by AbPP. It interacts with AbPP to play a role in brain development. AIDA-1 also interacts with coilin in Cajal bodies to regulate pre-mRNA splicing. |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |