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(R)-(+)Etomoxir Na

Overview
Catalog # bs-83409c-25mg
Product Name (R)-(+)Etomoxir Na
Specifications
Storage Buffer White solid
Storage Condition -20°C
Target
Product Information Etomoxir (828934-41-4) is an irreversible inhibitor of mitochondrial carnitine palmitoyl transferase 1 (CPT1).1 It is widely used to study fatty acid oxidation. Etomoxir has been investigated as a therapeutic agent for heart disease2, diabetes3, and cancer4,5. Use of etomoxir in concentrations greater than 5 µM induces acute production of ROS with associated evidence of severe oxidative stress in proliferating T cells indicating a loss of specificity for CTP1 at these concentrations.6 200 µM etomoxir inhibited complex I of the electron transport chain.7
Description CAS Number: 828934-41-4

Chemical Name: Carnitine palmitoyltransferase inhibitor

Molecular Weight: 320.74

Formula: C15H18ClO4·Na

Solubility: DMSO (5 mg/ml)

Physical Properties: White solid

Purity: 98% by HPLC, NMR (Conforms)