(R)-(+)Etomoxir Na
| Overview | |
| Catalog # | bs-83409c-25mg |
| Product Name | (R)-(+)Etomoxir Na |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Etomoxir (828934-41-4) is an irreversible inhibitor of mitochondrial carnitine palmitoyl transferase 1 (CPT1).1 It is widely used to study fatty acid oxidation. Etomoxir has been investigated as a therapeutic agent for heart disease2, diabetes3, and cancer4,5. Use of etomoxir in concentrations greater than 5 µM induces acute production of ROS with associated evidence of severe oxidative stress in proliferating T cells indicating a loss of specificity for CTP1 at these concentrations.6 200 µM etomoxir inhibited complex I of the electron transport chain.7 |
| Description | CAS Number: 828934-41-4 Chemical Name: Carnitine palmitoyltransferase inhibitor Molecular Weight: 320.74 Formula: C15H18ClO4·Na Solubility: DMSO (5 mg/ml) Physical Properties: White solid Purity: 98% by HPLC, NMR (Conforms) |
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