Phenylhexyl isothiocyanate
| Overview | |
| Catalog # | bs-83106c-5-mg |
| Product Name | Phenylhexyl isothiocyanate |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Isothiocyanate constituents of cruciferous vegetables are potent chemopreventive agents for carcinogen-induced cancers in rodents.1 PHITC was the most potent in a series of synthetic arylalkyl isothiocyanates at inhibition of tumorigenicity by NNK, a tobacco-derived nitrosamine, in a mouse model.2 It was also found to induce apoptosis and inhibit leukemia cell growth in vivo3 and was shown to have dual function as a histone deacetylase inhibitor and hypomethylating agent4. PHITC was also shown to restore the activity of mutant p53 and reactivate the p53 pathway in human myeloid leukemia M2 cells.5 |
| Description | CAS Number: 133920-06-6 Chemical Name: 6-Isothiocyanatohexylbenzene Molecular weight: 219.35 Formula: C13H17NS Solubility: DMSO (25 mg/ml) Physical Properties: Colorless to pale yellow liquid Purity: >98% by TLC NMR (Conforms) |
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