α-Mangostin
Applications
| Overview | |
| Catalog # | bs-82678c-10-mg |
| Product Name | α-Mangostin |
| Applications | Life Science |
| Specifications | |
| Conjugation | Unconjugated |
| Storage Buffer | Off-white solid |
| Storage Condition | -20°C |
| Target | |
| Background | α-Mangostin is a xanthone natural product that has historically been used in traditional folk medicine.1 It is a potent agonist of human STING (Stimulator of Interferon Genes) and also weakly activates mouse STING.2 Induces IFN- production and repolarizes human monocyte-derived M2 macrophages to M1. Improves insulin secretion and protects INS-1 cells from streptozotocin-induced damage.3 Suppresses the metastasis of human renal carcinoma cells.4 Synergizes with kinase inhibitors in suppression of proliferation of SK-MEL-2 malignant melanoma cells.5 |
| Application Dilution | |
| Life Science | N/A |
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