α-Mangostin

Overview
Catalog #	bs-82678c-10-mg
Product Name	α-Mangostin
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	α-Mangostin is a xanthone natural product that has historically been used in traditional folk medicine.1 It is a potent agonist of human STING (Stimulator of Interferon Genes) and also weakly activates mouse STING.2 Induces IFN- production and repolarizes human monocyte-derived M2 macrophages to M1. Improves insulin secretion and protects INS-1 cells from streptozotocin-induced damage.3 Suppresses the metastasis of human renal carcinoma cells.4 Synergizes with kinase inhibitors in suppression of proliferation of SK-MEL-2 malignant melanoma cells.5
Description	CAS Number: 6147-11-1 Chemical Name: 1,3,6-Trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one Molecular weight: 410.46 Formula: C24H26O6 Solubility: DMSO (50 mg/ml) Physical Properties: Yellow solid Purity: 98% by HPLC NMR (Conforms)