AC1903

Overview
Catalog #	bs-82669c-10-mg
Product Name	AC1903
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	A potent and selective TRPC5 blocker. Suppresses severe proteinuria and prevents podocyte loss in a transgenic rat model of focal segmental glomerulosclerosis. It also provided therapeutic benefit in a rat model of hypertensive proteineuric kidney disease. The use of this selective tool compound provided a mechanistic rationale for targeting TRPC5 channels in progressive chronic kidney diseases and paves the way for the discovery of new therapeutics. Active in vivo.
Description	CAS Number: 831234-13-0 Chemical Name: 1-Benzyl-1H-benzoimidazol-2-yl)-furan-2-ylmethyl-amine Molecular weight: 303.36 Formula: C19H17N3O Solubility: DMSO (30 mg/ml) Ethanol (25 mg/ml) Physical Properties: Beige solid Purity: 98% by TLC NMR (Conforms)