Leu-Leu-OMe HBr
| Overview | |
| Catalog # | bs-82653c-20-mg |
| Product Name | Leu-Leu-OMe HBr |
| Specifications | |
| Storage Buffer | Crystalline solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Leu-Leu-OMe is a lysosomal damaging agent (lysosomotropic). It is condensed into a membranolytic polymer via the transpeptidase action of cathepsin C within lysosomes.1,2 May be used to induce a lysosomal damage model in cells.3,4 LLOMe-induced lysosomal damage elicits ubiquitin puncta formation on lysosomes1. Induces apoptosis in human mast cells via lysosome destabilization leaving fibroblasts and HEK-293 cells largely resistant5. Induces lysophagy.4 |
| Description | CAS Number: 16689-14-8 Chemical Name: Leucyl-leucine methyl ester hydrobromide Molecular weight: 339.27 Formula: C13H26N2O3 HBr Solubility: DMSO (35 mg/ml) Water (40 mg/ml) Physical Properties: White solid Purity: 98% by HPLC NMr (Conforms) |
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