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2',3'-cGAMP

Overview
Catalog # bs-82354c-1-mg
Product Name 2',3'-cGAMP
Specifications
Storage Buffer White solid
Storage Condition -20°C
Target
Product Information 2',3'-cGAMP (CAS 1441190-66-4) is an endogenous STING (stimulator of interferon genes) agonist.1 Produced from ATP and GTP via the action of cGMP-AMP synthase (cGAS) which acts as a cytosolic DNA sensor.2,3 Induces autophagy which is a mechanism for clearance of DNA and viruses in the cytosol.4 DNA damage stimulates 2’,3’-cGAMP which stimulates an inflammatory response.5
Description CAS Number: 1441190-66-4

Chemical Name: Adenylyl-(3’5’)-2’guanylic acid, cyclic nucleotide, disodium salt

Molecular weight: 718.38

Formula: C20H22N10O13P2·2Na

Solubility: DMSO (>25 mg/ml) Water (10 mg/ml)

Physical Properties: White solid

Purity: 98% by HPLC NMR (Conforms)