2',3'-cGAMP
| Overview | |
| Catalog # | bs-82354c-1-mg |
| Product Name | 2',3'-cGAMP |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | 2',3'-cGAMP (CAS 1441190-66-4) is an endogenous STING (stimulator of interferon genes) agonist.1 Produced from ATP and GTP via the action of cGMP-AMP synthase (cGAS) which acts as a cytosolic DNA sensor.2,3 Induces autophagy which is a mechanism for clearance of DNA and viruses in the cytosol.4 DNA damage stimulates 2’,3’-cGAMP which stimulates an inflammatory response.5 |
| Description | CAS Number: 1441190-66-4 Chemical Name: Adenylyl-(3’5’)-2’guanylic acid, cyclic nucleotide, disodium salt Molecular weight: 718.38 Formula: C20H22N10O13P2·2Na Solubility: DMSO (>25 mg/ml) Water (10 mg/ml) Physical Properties: White solid Purity: 98% by HPLC NMR (Conforms) |
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