2-APB

Overview
Catalog #	bs-82136c-100-mg
Product Name	2-APB
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	An IP3 receptor antagonist (IC50=42 μM).1 Inhibits store-operated Ca2+ channels at high concentrations (50 μM) but stimulates at low concs. (<10 μM).2 Modulates TRP channels, blocking TRPC1, TRPC3, TRPC5, TRPC6, TRPV6, TRPM3, TRPM7, TRPM8, TRPP2 and at higher concentrations, activating TRPV1, TRPV2, TRPV3.3,4 Also inhibits selected GAP junction subtypes.5
Description	CAS Number: 524-95-8 Chemical Name: 2-Aminoethoxydiphenyl borate Molecular weight: 225.1 Formula: C14H16BNO Solubility: DMSO (20 mg/ml) Ethanol (5 mg/ml) Physical Properties: White solid Purity: 98% by TLC, NMR Conforms