Overview |
bs-8183R-APC |
COMMD3 Polyclonal Antibody, APC Conjugated |
WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
Mouse |
Human, Rat, Dog, Cow |
Specifications |
APC |
Rabbit |
KLH conjugated synthetic peptide derived from human COMMD3 |
101-195/195 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
23412 |
Q9UBI1 |
Cytoplasm, Nucleus |
BUP; C10orf8; COMM domain-containing protein 3; Protein Bup; Protein PIL; COMMD3 |
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). May down-regulate activation of NF-kappa-B (PubMed:15799966). Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits (PubMed:23637203). |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |