A-803467
| Overview | |
| Catalog # | bs-80044C |
| Product Name | A-803467 |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | RT |
| Target | |
| Product Information | Molecular Weight:357.80 Formula:C19H16ClNO4 Purity:>98% Solubility:Soluble in DMSO (up to 15 mg/ml) or in Ethanol (up to 2 mg/ml). Chemical Name:5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide |
| Description | Potent, selective inhibitor of the TTX-resistant voltage-gated sodium channel Nav1.8. Nav1.8 is preferentially expressed in sensory neurons, and inhibition attenuates both inflammatory and neuropathic pain in a variety of animal models. IC50's for rat and human Nav1.8 are 140 nM and 8.0 nM respectively. |
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