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AICDA Polyclonal Antibody, PE Conjugated

Applications

  • WB

Predicted Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-7855R-PE
Product Name AICDA Polyclonal Antibody, PE Conjugated
Applications WB
Predicted Reactivity Human, Mouse, Rat
Specifications
Conjugation PE
Host Rabbit
Source KLH conjugated synthetic peptide derived from human AICDA
Immunogen Range 101-198/198
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 57379
Swiss Prot Q9GZX7
Subcellular location Nucleus
Synonyms AID; ARP2; CDA2; HIGM2; HEL-S-284; Single-stranded DNA cytosine deaminase; Activation-induced cytidine deaminase; Cytidine aminohydrolase; AICDA
Background Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class-switch recombination in B-lymphocytes. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.
Application Dilution
WB 1:500-2000