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RACGAP1(Ser387) Polyclonal Antibody, AbBy Fluor® 750 Conjugated

Applications

  • WB
  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Human
  • Mouse
  • Others

Predicted Reactivity

  • Rat
  • Dog
  • Cow
Overview
Catalog # bs-7767R-BF750
Product Name RACGAP1(Ser387) Polyclonal Antibody, AbBy Fluor® 750 Conjugated
Applications WB, IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity Human, Mouse, Others
Predicted Reactivity Rat, Dog, Cow
Specifications
Conjugation AbBy Fluor® 750
Host Rabbit
Source KLH conjugated synthetic phosphopeptide derived from human RACGAP1 around the phosphorylation site of Ser387.
Modification Site Ser387
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 29127
Subcellular location Cytoplasm, Nucleus
Synonyms RACGAP1 phospho S387; p-RACGAP1S387; p-RACGAP1Ser387; GAP; Gap1; GTPase activating protein; HsCYK 4; HsCYK4; ID GAP; KIAA1478; MgcRacGAP; Rac GTPase activating protein 1; RACGAP 1.
Background Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.
Application Dilution
WB 1:300-5000
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200