6-(4-Acetamido-1,8-naphthalamido) hexanoic acid
| Overview | |
| Catalog # | bs-75809c-10mg |
| Product Name | 6-(4-Acetamido-1,8-naphthalamido) hexanoic acid |
| Specifications | |
| Storage Buffer | Solid |
| Storage Condition | Stable for 2 years after receipt when stored at -20°C. |
| Target | |
| Product Information | CAS Number: 172227-59-7 Molecular formula: C20H20N2O5 Molecular weight: 368.38 Purity: >95% (HPCE) Appearance: Solid. Solubility: Soluble in water or DMSO. InChiKey: RCZAYEHQRFPFSH-UHFFFAOYSA-N SMILES: CC(=O)NC1=CC=C2C(=O)N(CC(O)=O)C(=O)C3=C2C1=CC=C3 |
| Description | The highly fluorescent label 4-acetylamino-1,8-naphthalimide-N-caproic acid has two fused benzene rings containing a closed anhydride ring and therefore is a flat and planar molecule which can easily intercalate or act as a groove binder with DNA/RNA sequences. For the study of in situ hydridization with complementary synthetic oligonucleotides (ODNs), tagging with non-radioactive labels has gained importance, not only for medical diagnostics or clinical genetics, but also detection and isolation of DNA for research purposes. The pentamethylene chain in 6 acts as a linker molecule and keeps the target at a reasonable distance to avoid direct interaction with oligonucleotides. |
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