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22-NHC . hydrochloride

Overview
Catalog # bs-75448c-1mg
Product Name 22-NHC . hydrochloride
Specifications
Storage Buffer Solid
Storage Condition Stable for 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
Target
Product Information CAS Number: 360068-87-7 or 3915-24-0 (free base)

Molecular formula: C26H45NO . HCl

Molecular weight: 387.6 . 36.5

Purity: >98% (NMR)

Appearance: White solid.

Solubility: Soluble in DMSO.

InChiKey: GDMMRLCQKPSXQG-USNJAYOWSA-N

SMILES: [Cl-].[H][C@@]12CC[C@H]([C@H](C)[NH2+]CCC(C)C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@@H](O)CC[C@]12C
Description Aza-steroid [1]. Hedgehog signaling inhibitor [1]. Competes with 20(S)-OHC for access to the cysteine-rich domain in Smoothened (Smo) [1]. For control compound see 22-NHC (inactive isomer) (Prod. No. bs-75449C).