6BIO
Overview | |
Catalog # | bs-75386c-1mg |
Product Name | 6BIO |
Specifications | |
Storage Buffer | Solid |
Storage Condition | Stable for 2 years after receipt when stored at -20°C. |
Target | |
Product Information | CAS Number: 667463-62-9 Molecular formula: C16H10BrN3O2 Molecular weight: 356.2 Purity: >98% (NMR) Appearance: Dark red solid. Solubility: Soluble in DMSO. InChiKey: DDLZLOKCJHBUHD-WAVHTBQISA-N SMILES: O\N=C1\C(\NC2=CC=CC=C\12)=C1\C(=O)NC2=C1C=CC(Br)=C2 |
Description | Phosphoinositide-dependent kinase 1 (PDK1) inhibitor. Potent, reversible and ATP-competitive glycogen synthase kinase-3alpha/beta (GSK-3alpha/beta) inhibitor. JAK/STAT3 signaling inhibitor. Apoptosis inducer. Potent antiproliferative agent in malignant lymphoid cell. Antimetastatic agent. Potent chemosensitizing agent fighting TRAIL resistant cancer cells. |