Overview |
bs-7515R-Cy3 |
KLHL20 Polyclonal Antibody, Cy3 Conjugated |
IF(IHC-P), IF(IHC-F), IF(ICC) |
Rat |
Human, Mouse, Cow, Sheep, Chicken, Rabbit |
Specifications |
Cy3 |
Rabbit |
KLH conjugated synthetic peptide derived from human KLHL20 |
13-100/609 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
27252 |
Cytoplasm, Nucleus |
Kelch like ECT2 interacting protein; Kelch like protein 20; Kelch like protein X; Kelch mot containing protein; Kelch-like ECT2-interacting protein; Kelch-like protein 20; Kelch-like protein X; KHLHX; KLEIP; KLH20CHUMAN; KLHL20; KLHLX; RP3-383J4.3. |
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in interferon response. The BCR(KLHL20) E3 ubiquitin ligase complex mediates the ubiquitination of DAPK1, leading to its degradation by the proteasome, thereby acting as a negative regulator of apoptosis. Also acts as a regulator of endothelial migration during angiogenesis by controlling the activation of Rho GTPases. |
Application Dilution |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |