Overview |
bs-7451R-BF750 |
Histone H3 (acetyl K27) Polyclonal Antibody, AbBy Fluor® 750 Conjugated |
WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
Human, Rat |
Specifications |
AbBy Fluor® 750 |
Rabbit |
KLH conjugated Synthesised acetylpeptide derived from human Histone H3 around the acetylation site of K27 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
8290 |
P68431 |
Nucleus |
acetyl H3; Histone H3(acetyl k27); H3K27; H 3; H3 3 Like Sequence MH921; H3 3A; H3; H3 Histone; H3 Histone Family Member E Pseudogene; H3.4; H3/A; H3/g; H31_HUMAN; H3F3; H3FA; H3FT; H3t; HIST1H3J; HIST3H3; Histone cluster 1, H3a; Histone H3 3 Pseudogene; Histone H3.1; Histone H3.3; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; |
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |