Overview |
bs-7057R-APC |
Glucokinase regulatory protein Antibody, APC Conjugated |
WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
Rat |
Human, Mouse, Dog, Pig, Horse, Rabbit |
Specifications |
APC |
Rabbit |
KLH conjugated synthetic peptide derived from human GCKR |
121-220/625 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
2646 |
Q14397 |
Nucleus |
GKRP; FGQTL5; Glucokinase regulatory protein; Glucokinase regulator; GCKR |
Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity. |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |