Synaptophysin 2 Antibody

Overview
Catalog #	bs-70273R
Product Name	Synaptophysin 2 Antibody
Applications	WB, ICC
Specificity	Specific for endogenous levels of the ~38 kDa Synaptophysin 2 protein.
Reactivity	Mouse, Rat
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	Synthetic peptide corresponding to amino acid residues from the C-terminal region of rat synaptophysin 2, conjugated to keyhole limpet hemocyanin (KLH).
Clonality	Polyclonal
Isotype	IgG
Concentration	Lot Dependent
Purification	Antigen Affinity purification from Pooled whole antiserum
Storage Buffer	10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Storage Condition	Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
Target
Gene ID	66030
Swiss Prot	P22831
Synonyms	DKFZp686G0883 antibody, MGC26651 antibody, SPO antibody, Synaptophysin 2 antibody, Synaptoporin antibody, Synpr antibody, SYNPR_HUMAN antibody
Background	Synaptophysin 2, also known as Synaptoporin, is a component of the synaptic vesicle membrane and thought to play an important role in synaptic vesicle trafficking (Dai et al., 2003). It is highly homologous to Synaptophysin 1, yet differs in expression. Whereas Synaptophysin 1 is ubiquitously expressed, Synaptophysin 2 is concentrated in the mossy fiber synapses of the hippocampus (Grabs et al., 1994; Singec et al., 2002).
Application Dilution
WB	1:300-5000
ICC	1:100-500