| Overview |
| bs-70235R |
| PSD-95 Antibody |
| WB |
| Specific for endogenous levels of the ~95 kDa PSD-95 protein. |
| Mouse, Rat |
| Human, Bovine, Zebrafish, Non-Human Primate |
| Specifications |
| Unconjugated |
| Rabbit |
| Synthetic peptide corresponding to amino acid residues from the N-terminal region of rat PSD-95, conjugated to keyhole limpet hemocyanin (KLH). |
| Polyclonal |
| IgG |
| Lot Dependent |
| Antigen Affinity purification from Pooled whole antiserum |
| 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol. |
| Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C. |
| Target |
| 29495 |
| P31016 |
| Discs large homolog 4 antibody, Disks large homolog 4 antibody, DLG 4 antibody, Dlg4 antibody, DLG4_HUMAN antibody, FLJ97752 antibody, FLJ98574 antibody, Human post synaptic density protein 95 antibody, Post synaptic density protein 95 antibody, Postsynaptic density protein 95 antibody, PSD 95 antibody, PSD-95 antibody, PSD95 antibody, SAP 90 antibody, SAP-90 antibody, SAP90 antibody, Synapse associated protein 90 antibody, Synapse-associated protein 90 antibody, Tax interaction protein 15 antibody |
| PSD-95 is a very prominent component of the postsynaptic densities of synapses. It contains three PDZ domains which play key roles in its interactions with other proteins in the synapse. It has been proposed that these PDZ domains organize glutamate receptors and their associated signaling proteins and determine the size and strength of synapses (Kim and Sheng, 2004). Recent work suggests that interaction of the NMDAR with PSD-95 via these PDZ domains can be regulated by phosphorylation (Chung et al., 2004). |
| Application Dilution |
| WB |
1:300-5000 |
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