PEBP (phosphatidylethanolamie binding protein) Antibody

Applications

Reactivity

Overview
Catalog #	bs-70218R
Product Name	PEBP (phosphatidylethanolamie binding protein) Antibody
Applications	WB
Specificity	Specific for endogenous levels of the ~22 kDa PEBP protein.
Reactivity	Rat
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	Purified native rat PEBP
Clonality	Polyclonal
Isotype	IgG
Concentration	Lot Dependent
Purification	Neat whole antiserum
Storage Buffer	Neat whole antiserum
Storage Condition	Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
Target
Gene ID	31042
Swiss Prot	P31044
Synonyms	Epididymis luminal protein 210 antibody, Epididymis secretory protein Li 34 antibody, Epididymis secretory protein Li 96 antibody, HCNP antibody, HCNPpp antibody, HEL 210 antibody, HEL S 34 antibody, HEL S 96 antibody, Hippocampal cholinergic neurostimulating peptide antibody, Neuropolypeptide h3 antibody, PBP antibody, PEBP antibody, PEBP 1 antibody, PEBP-1 antibody, Pebp1 antibody, PEBP1_HUMAN antibody, Phosphatidylethanolamine binding protein antibody, Phosphatidylethanolamine binding protein 1 antibody, Prostatic binding protein antibody, Prostatic-binding protein antibody, R kip antibody, Raf kinase inhibitor protein antibody, Raf kinase inhibitory protein antibody, RKIP antibody
Background	Phosphatidylethanolamine binding protein (PEBP), also known as Raf kinase inhibitory protein (RKIP) is a highly conserved multifunctional protein that modulates the Raf/MAPK signaling cascade and has been implicated as a suppressor of metastatic cancer (Trakul N et al., 2005). PEBP has been shown to not only inhibit cell proliferation but also to induce differentiation of human keratinocytes (Yamazaki et al., 2004). Dysregulation of calpain activity results in cellular degeneration in conditions such as Alzheimer’s disease and recently PEBP has been identified as a potential in vivo calpain substrate (Chen at al., 2006).
Application Dilution
WB	1:300-5000