| Overview |
| bs-70035R |
| cdc2 (Tyr15) Antibody |
| WB |
| Specific for endogenous levels of the ~34 kDa cdc2 protein phosphorylated at Tyr15. Immunolabeling is completely eliminated by treatment with λ-phosphatase. |
| Human, Mouse, Xenopus |
| Rat, Zebrafish |
| Specifications |
| Unconjugated |
| Rabbit |
| Synthetic phospho-peptide corresponding to amino acid residues surrounding Tyr15 of rat cdc2, conjugated to keyhole limpet hemocyanin (KLH). |
| Tyr15 |
| Polyclonal |
| IgG |
| Lot Dependent |
| Antigen Affinity purification from Pooled whole antiserum |
| 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol. |
| Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C. |
| Target |
| 54237 |
| P39951 |
| Cdc 2 antibody, Cdc2 antibody, CDC28A antibody, CDK-1 antibody, CDK 1 antibody, CDK1 antibody, CDK1_HUMAN antibody, CDKN1 antibody, CELL CYCLE CONTROLLER CDC2 antibody, Cell division control protein 2 antibody, Cell division control protein 2 homolog antibody, Cell division cycle 2 G1 to S and G2 to M antibody, Cell division protein kinase 1 antibody, Cell Divsion Cycle 2 Protein antibody, Cyclin Dependent Kinase 1 antibody, Cyclin-dependent kinase 1 antibody, DKFZp686L20222 antibody, MGC111195 antibody, p34 Cdk1 antibody, p34 protein kinase antibody, P34CDC2 antibody |
| Cdc2 is a highly conserved protein serine kinase that plays a key role in regulation of the cell cycle (Maller, 1991). The ability of cdc2 to exercise control over the cell cycle is dependent upon the phosphorylation of Tyr-15 in cdc2 (Nakamizo et al., 2002). cdc2 expression in brain has been linked to both neurogenesis and apoptosis (Konishi and Bonni, 2003; Dranovsky et al., 2001; Okano et al., 1996). |
| Application Dilution |
| WB |
1:300-5000 |
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