| Overview |
| bs-6989R |
| G6PDH Polyclonal Antibody |
| ELISA, IHC-P, IHC-F |
| Human, Mouse, Rat, Dog, Horse, Rabbit |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human G6PDH |
| 321-420/791 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 9563 |
| Cytoplasm |
| 6 phosphogluconolactonase; 6-phosphogluconolactonase; 6PGL; H6PD; DKFZp686A01246; G6PD H form; G6PDH; G6PE_HUMAN; GDH; H6PD; GDH/6PGL endoplasmic bunctional protein; Glucose 1 dehydrogenase; Glucose 6 phosphate dehydrogenase salivary; Glucose dehyrogenase; Gpd1; H6pd; Hexose 6 phosphate dehydrogenase; Hexose-6-phosphate dehydrogenase; MGC87643. |
| H6PD (hexose-6-phosphate dehydrogenase, GDH/6PGL endoplasmic bifunctional protein) is a 789 amino acid protein encoded by the human gene H6PD. The N-terminal section of H6PD belongs to the glucose-6-phosphate dehydrogenase family, while the C-terminal section belongs to the glucosamine/galactosamine-6-phosphate isomerase family, 6-phosphogluconolactonase subfamily. H6PD is responsible primarily for the oxidation of glucose-6-phosphate and glucose. It also oxidizes other hexose-6-phosphates. H6PD catalyzes the conversion of glucose 6-phosphate to 6-phosphogluconolactone within the lumen of the endoplasmic reticulum, thereby generating reduced nicotinamide adenine dinucleotide phosphate. Reduced nicotinamide adenine dinucleotide phosphate is a necessary cofactor for the reductase activity of 11-hydroxysteroid dehydrogenase type 1, which converts hormonally inactive cortisone to active cortisol (in rodents, 11-dehydrocorticosterone to corticosterone). |
| Application Dilution |
| ELISA |
1:500-1000 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
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