Overview |
bs-6898R-PE-Cy5.5 |
Mitochondrial ribosomal protein L11 Antibody, PE-Cy5.5 Conjugated |
WB |
Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit |
Specifications |
PE-Cy5.5 |
Rabbit |
KLH conjugated synthetic peptide derived from human Mitochondrial ribosomal protein L11 |
31-130/192 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
65003 |
Cytoplasm |
39S ribosomal protein L11, mitochondrial; CGI113; CGI 113; L11mt; MRP L11; MRP-L11; RM11_HUMAN. |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode different isoforms. Pseudogenes corresponding to this gene are found on chromosomes 5q and 12q. [provided by RefSeq, Jul 2008]. |
Application Dilution |
WB |
1:300-5000 |