Overview |
bs-6649R-APC |
ADORA1 Polyclonal Antibody, APC Conjugated |
WB |
Human, Mouse |
Rat, Dog, Cow, Pig, Horse, Chicken, Rabbit |
Specifications |
APC |
Rabbit |
KLH conjugated synthetic peptide derived from human Adenosine A1 Receptor |
225-326/326 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
134 |
P30542 |
Cell membrane |
RDC7; Adenosine receptor A1; ADORA1 |
Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response, and the inhibition of protein synthesis. The Adenosine receptors, including Adenosine A1-R, Adenosine A2A-R, Adenosine A2B-R and Adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. Adenosine A1-R mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via Adenosine A2A-R. Collagen synthesis and total protein synthesis are inhibited in certain cells by Adenosine, acting via the A2B receptors. Activation of Adenosine A3-R inhibits the induction of TNF?and blocks the endotoxin CD14 receptor signal transduction pathway. |
Application Dilution |
WB |
1:300-5000 |